“Aspartame Sensitivity? A Double Blind Randomised Crossover Study,” published in the journal PLOS One, is the latest in a long line of studies that confirm the safety of aspartame.
Although some people have reported adverse reactions to aspartame (such as headaches, anxiety, or seizures), labeled as “aspartame sensitivity,” these experiences have not been validated by credible scientific research.
This latest double-blind crossover study investigated the theory of aspartame sensitivity by comparing the psychological and physiological effects of aspartame consumption in two different groups. Forty-eight individuals who self-identified as aspartame-sensitive were age and gender matched with 48 non-sensitive individuals. Both groups were fed snack bars containing aspartame and bars containing a placebo, and their physiological and psychological reactions were compared.
Psychological and visual symptoms were self-reported, and the researchers acknowledged this as a potential limitation of the study. The researchers found no evidence of any acute adverse reactions to aspartame consumption, and no evidence to support anecdotes of aspartame sensitivity. Aspartame has a long record of safe use in the U.S., and its safety has been affirmed by international regulatory authorities, including European Food Safety Authority (EFSA), which recently published an opinion on aspartame safety.
Have more questions on aspartame or low-calorie sweeteners? See our resources below:
Low-Calorie Sweeteners—tagged content